MKTG 406 = MID EXAM & FINAL EXAM Assignment Example | Topics and Well Written Essays - 6250 words

MKTG 406 = MID EXAM & FINAL EXAM - Assignment Example This can be anything, a stable income or job, etc. The next level of needs which is requirement by the person is the need of love and society. The sense of belongingness is his concern at this stage. He or she starts a family and wants to become a part of the society. The next step in the level of needs is the requirement of self esteem. The person wishes to have a successful carrier and wants to be known for his success. He or she thinks himself or herself to be special. Once the self esteem stage has been achieved, the person goes on to the final level of needs known as the self-actualization. This need is way more important than anything; the aspirations come into play over here. Now having discussed the Maslow’s Hierarchy, let us go on to relating these 5 levels of needs with marketing. As the person goes through the different level of needs, he is always influenced by the some products or services at some point of time. In the first step where the person is looking for the basic needs such as food and shelter, he or she will try to select a food is cheap at the same time nutritious, the advertisement displayed or shown will play a major role in his choice. Similarly, in the second stage the person is looking for security and safety. The security can job or life insurance. Again in this situation, the various firms will try to divert his or her mind to purchase their product or services by saying how different and exclusive their services are. This way the person may or may not get manipulated in purchasing the above services. Again in the next three stages also there are various forms of marketing involved which are used against the consumers. For e xample Vodafone might call a person saying that he or she is their most valued customer and that is he or she is being offered a new mobile connection free of charge. This in return tends to affect the person emotionally and the person will most likely go ahead with the deal. Another

The Export-Led Growth Model Essay Example | Topics and Well Written Essays - 1750 words

The Export-Led Growth Model - Essay Example China’s model is rooted in the double transition of demographic and structural transformation. China economy has tremendously managed the double-digit growth rates from the period when it began economic transformation. This enabled the country to move from a planned to a mixed economy where the market plays the significant roles in resource allocation. Thus, despite the political, social and economic problems associated with the rapid growth in China economies, export-led growth has tremendously enabled China to increase their profitability levels, balance their finances, exceed their debts and trigger their export growth rate.Export-led growth model have been successful in many economies that employ this model for creating economic transformation. The export-led model is significant because it has enabled many economies to increase their profitability levels, balance their finances and exceed their debts. China has benefited from the export-led model since they started using it because this model has enabled them to increase their profitability levels. China was ranked the second largest economies that have emerged and improved in terms of economic performance in the global market. This model has not only enabled them to increase their profitability level but also to balance their finances; thus enabling China to emerge as the successful economies in Asian markets.It has also triggered export growth rate in the China market; thus creating higher export levels.... This model has not only enabled them to increase their profitability level but also to balance their finances; thus enabling China to emerge as the successful economies in Asian markets. It has also triggered export growth rate in the China market; thus creating higher export levels in a rising spiral cycle. For instance, the GDP (Gross Domestic Products) in China market expanded by 2%, in the year 2012 and indicated in figure 1 below. Historically, the GDP average rate was 2.06% from 2011 and the record indicated the 1.50 % low in 2012 as indicated in figure1 below. China is one of the second economies after the United States that has improved their export rate in the global market. China has varied industries that export multiple products to diverse countries across the globe. The rise of population growth rate has enabled them to improve their economic performance because of rich markets because of both rich markets both in the domestic and the international markets. For instance, the National Bureau of Statistics of China reveals that the GDP for the China economy was 51,932.2 billion in the year 2012; thus contributing to economic expansion of 7.9 percent. Figure 1: GDP Growth Rate in China markets The implementation model of export-led growth has significantly contributed to increased rapid growth in the China markets. For the last three decades, China economy has grown to the average rates, which exceed 9%; thus, it is widely admired by other nations (Razmi 2008, p. 1). Furthermore, the growth has been accompanied by the reduction levels in poverty; thus enabling the China market to be ranked among the leading and emerging economies in the Asian nations. However, the trajectory of rapid growth in China has created political, social made

Fibroblast Growth Factors (FGFs) in Neural Induction

Fibroblast Growth Factors (FGFs) in Neural Induction Abstract Neural induction represents the first stage in the formation of the vertebrate nervous system from embryonic ectoderm. Fibroblast Growth Factors (FGFs), initially identified for their mitogenic and angiogenic roles in bovine brain extracts, are now known to have many developmental roles in particular that of neural induction, comprising of a family of 22 FGFs. Spemann and Mangold (1924) pioneered the study of neural induction through the identification of the organizer. Early work in amphibians suggested that neural fate was instructed by signals from Spemanns organiser or dorsal mesoderm. Over a decade ago, the default model proposed that neural induction was the direct consequence from inhibition of bone morphogenetic proteins (BMPs) found in Xenopus laevis, not taking into consideration neural induction in avian embryos. Consequently many experimental studies, in the chick, subsequent to this finding conflicted the idea that BMP inhibition was the only necessary step required suggesting that FGFs were required at an earlier stage prior to BMP inhibition. Much controversy has surrounded the role of FGFs in neural induction but now it is widely accepted to have a role in both amphibians and amniotes. Fibroblast Growth Factors in neural induction Structure and Function: FGFs broken down Fibroblast Growth Factors (FGFs) regulate a vast array of developmental processes, including, limb development, neural induction and neural development (Bà ¶ttcher and Niehrs, 2005). FGFs play an important role in development of an organism by regulating cellular differentiation, proliferation and migration and are involved in tissue-injury repair (Itoh and Ornitz, 2004). The early FGFs, FGF1 and FGF2 (also known as acidic and basic FGF, respectively) were first discovered from bovine brain and pituitary extracts and identified for their mitogenic and angiogenic activities (Gospodarowicz et al., 1974). Additionally, a number of family members were found revealing a total of 22 FGFs in humans ranging from 17 to 34 kDa in molecular mass in vertebrates. The nomenclature extends to FGF23 but in humans FGF19 is the equivalent to mouse Fgf15 (Ornitz and Itoh, 2001). Also the FGFs have been organised into seven subfamilies based on sequence comparisons. FGFs show conservation through species, especially across the vertebrate species in gene structure and amino-acid sequence. FGF sequences are yet to be found in unicellular organisms such as yeast (Saccharomyces cerevisiae) and bacteria (Escherichia Coli) (Itoh and Ornitz, 2004). Interestingly, an Fgf-like gene has been encoded in the nuclear polyhedrosis virus genome (Ayres et al., 1994). In protostomes, there are far fewer FGFs in contrast to vertebrates, as two (let-756 and egl-17) have been found in Caenorhabditis elegans and three (branchless, pyramus and thisbe) in Drosophila (Mason, 2007). Most FGFs have amino-terminal signal peptides (Fig. 1 (a)) and are secreted from cells. FGFs 9, 16 and 20 lack this signal peptide but nevertheless are still secreted (Ornitz and Itoh, 2001). FGF1 and FGF2 lack these signal sequences and are secreted by non-canonical pathways, however they can be found on the cell surface and within the extracellular matrix. Golfarb (2005) suggests that FGFs 11-14 do not interact with FGF receptors (FGFRs) and are not secreted but instead localise to the cell nucleus. Fig. 1 (above) illustrates the structural features of the FGF polypeptide (a). A signal sequence (shaded grey) can be seen here within the amino terminus and is present in most FGFs. All FGFs contain a core region (Fig. 1 (a)) containing around 120 amino acids of which 6 are identical amino acids residues and 28 are highly conserved (Goldfarb, 1996). The black boxes (numbered 1 to 12) represent the location of ÃŽ ² strands within the core. The three dimensional structure of FGF2 (b) can also be seen where the heparin binding region (yellow) includes residues between ÃŽ ²1 and ÃŽ ²2 strands and in ÃŽ ²10 and ÃŽ ²11 strands. FGFs have a high affinity for heparan sulfate proteoglycans (HSPG) and require heparan sulphate to activate one of four transmembrane receptor tyrosine kinases (FGFR1-4) in all vertebrates. FGFR5 has been identified recently, however most action is mediated via FGFR1-4 (Powers et al., 2000). FGFRs are membrane associated class IV receptor tyrosine kinases (RTKs). The FGFR tyrosine kinase receptors (Fig. 2 B) include 3 immunoglobulin (Ig) domains and a heparin binding sequence which requires heparan sulphate to be activated (McKeehan et al., 1998). HSPG are low affinity receptors that are unable to transmit a biological signal but act as co-factors for activation and regulation of an interaction between FGFs and FGFRs. Fig. 2 (above) illustrates a two dimensional generic FGF (A) and a FGFR (B) protein. The structure of a FGF (A) coincides with that of Fig. 1, containing a signal sequence in the amino-terminus and the conserved core region containing HSPG and receptor-binding sites. The main features of FGFRs (B) include 3-Immunoglobulin domains, an acidic box (AB) which lies between IgI and IgII, heparin-binding domain, Cell Adhesion Molecule (CAM)-homology domain, transmembrane domain and a split tyrosine kinase enzyme domain for catalytic activity and binding of adaptor proteins. The Ig domains in the extracellular region of a FGFR are required for FGF binding and regulate binding affinity and ligand specificity. Multiple alternative splicing that generates a range of FGFR1-4 receptor isoforms with transformed ligand binding properties provides diversity (Olsen et al., 2006). For example, FGF2 interacts with all four receptors FGFR1-4 whereas FGF7 only interacts with the FGFR2 IIIb isoform (a splice variant of FGF2; expressed in epithelial cells). Ligand-receptor binding specificity is affected by alternative splicing particularly in the C-terminal region of the third immunoglobulin loop in FGFR1-3 which produces IIIb or IIIc isoforms (Mason, 2007). Table 1 (below) illustrates the specificity of the FGF ligands for particular FGFR isoforms. This table is useful yet evidence from in vitro may appear misleading as in vivo involves influence from co-factors such as HSPG (Mohammadi et al., 2005). Table 1 (above) shows there are seven FGFR isoforms (FGFR1b; FGFR1c; FGFR2b; FGFR2c; FGFR3b; FGFR3c and FGFR4) that FGF1 through to FGF23 variously bind. Alternative mRNA splicing of FGFR1-3, particularly in the carboxy-terminal half of the third extracellular immunoglobulin loop (Ig-domain III), derives the b and c isoforms. HSPGs are necessary co-factors in activation of FGFRs by FGFs and evidence has found the ternary complex to comprise of FGF-FGFR-HSPG in a 2:2:1 ratio (Mohammadi et al., 2005). The co-binding of HSPG prevents proteolysis and thermal denaturation (Itoh and Ornitz, 2004). HSPG binding of FGF induces dimerization of FGFR, followed by transphosphorylation of receptor subunits, initiating an intracellular signalling cascade. FGF signalling: Its a cellular game Following formation of the FGF-HSPG-FGFR complex several downstream signalling pathways are activated (Fig. 3 below). This includes three pathways, the Ras/Mitogen-activated protein kinase (MAPK) pathway, Phosphoinositide 3-kinase (PI3K)/ Akt pathway and phospholipase C- (PLC )/ Ca2+/ protein kinase C (PKC) pathway. These pathways are mediated via docking proteins (such as FGF receptor substrate (FRS) and Grb2 in the Ras/MAPK pathway) that recruit downstream enzymes. The Ras/MAPK pathway (Fig. 3) is initiated via Grb2 (a docking protein) where its SH2 domain binds to the tyrosine phosphorylated FRS2 in response to activation of the FGFR receptor (Kouhara et al., 1997). Grb2 binds to SOS (son of sevenless; a guanine nucleotide exchange factor) via a SH3 domain on the Grb2 molecule. This Grb2-SOS complex activates SOS which promotes the dissociation of GDP from Ras so it is able to bind GTP for its activation. Activated Ras activates RAF (MAPKKK) which is normally held in a closed conf ormation by the 14-3-3 protein. Once activated, RAF phosphorylates and activates mitogen-activated and extracellular signal-regulated kinase (MEK (MAPKK)) which in turn phosphorylates ERK1/2 (MAPK). MAPK then translocates into the nucleus to phosphorylate specific transcription factors of the Ets family which in turn activate expression of FGF target genes. In addition, it is also evident from Fig. 3 that active ERK itself can antagonise FRS activity. Activation of the PI3K/Akt pathway (Fig. 3) is by binding of Gab1 (Grb2-associated-binding protein 1) to FRS2 indirectly via Grb2. In the presence of Gab1, activation of PI3K stimulates the Akt pathway which suggests FGFs have anti-apoptotic effects in the developing nervous system (Mason, 2007). In addition, PI3K can bind to a phosphorylated tyrosine residue of FGFR directly. The third way in which the PI3K/Akt pathway is activated is by activated Ras inducing membrane localisation of the PI3K catalytic subunit. PLC- /Ca2+/PKC pathway is also activated when a tyrosine residue is autophosphorylated in the carboxy terminal of the FGFR. PLC- hydrolyses phosphatidylinositol to produce inositol trisphosphate (IP3) and diacylglycerol (DAG) which stimulates calcium release and activates PKC, respectively. PKC has also been found to activate the Ras/MAPK pathway independent of Ras but dependent on c-Raf (Ueda et al., 1996). Fig. 3 also indicated that the final activated components, of the three signalling pathways mentioned, translocate into the nucleus to activate specific transcription factors of the Ets family (particularly Ets1, Pea3, and Erm) which activate expression of FGF target genes and in turn these feedback (Fig, 4) to regulate intracellular signalling (Dailey et al., 2005). Most of the proteins produced function as feedback inhibitors (as seen in Fig. 4), including Sprouty (Spry), Sef and MAP Kinase phosphatase 3 (MKP3) which modulate particularly the Ras/Erk pathway at different levels (Mason, 2007). In contrast, stimulation of the fibronectin leucine-rich transmembrane type III (XFLRT3) protein causes FGF signalling to be positively regulated (Bà ¶ttcher et al., 2003). Sprouty (Spry) was one of the first identified feedback regulators of the FGF pathway. Thisse and Thisse (2005) found Spry to antagonise FGF Signalling by gain and/or loss of function experiments in mouse. Spry acts at the level of Raf and/or Grb2 (Fig. 4). Gain and/or loss of function experiments in zebrafish demonstrated that Sef antagonises FGF signalling (Fig. 4) acting at level of MEK and ERK (Tsang et al., 2002). Mouse studies have suggested that FGFR signalling is required for Dusp6 transcription which codes for MKP3 (Ekerot et al., 2008). From this study it was also found that MKP3 acts as a negative regulator of ERK activity (as seen in Fig. 4). Sef and XFLRT3 are located at the membrane (Fig. 4) and carry out antagonising actions with FGFR directly. FGF signalling can be regulated at different levels, from the membrane all the way down to the level of phosphorylation of MAPK and it is important also to know that FGFs have been detected in the nucleus (Mason, 2007). Most of the downstream target genes as described earlier are feedback inhibitors (Spry, Sef and MKP3) but FGF signals are also known to interact with many other important pathways such as transforming growth factor-ÃŽ ² (TGF-ÃŽ ²), Hedgehog (HH), Notch and Wnt (Gerhart, 1999). Therefore, in conjunction with these, FGFs are responsible for development of most organs of the vertebrate body. In the nervous system, FGFs have been implicated to play a role in early developmental processes, such as neural induction, patterning and proliferation (Umemori, 2009). Neural induction: The Default Model Spemann and Mangold (1924) pioneered the study of neural induction, which is defined as the process by which naive ectodermal cells aquire a neural fate. Their work involved demonstrating that tissue from the dorsal lip of the frog Xenopus laevis blastopore could induce a second ectopic nervous system (Fig. 5 above left) when implanted onto the ventral side of a host gastrula embryo. The second ectopic nervous system was host derived indicating that the graft was important in determining cell fate. This region, located on the dorsal side of an amphibian embryo, was named the Spemann organizer as it could direct the neighbouring ectodermal cells to form nervous system instead of epidermis. Although the organizer (group of dorsal mesodermal cells) was found to be present in many species (Hamburger, 1988) it was the Xenopus laevis which gave an insight into the molecular events involved in neural induction in vertebrates (Hemmati-Brivanlou et al., 1994). This was particularly because amphibians were found to be ideal experimental models for the study of neural induction as neurulation initiated within twelve hours after fertilisation (Weinstein and Hemmati-Brivanlou, 1997). It was implied that signals from the organizer provide instructions to the ectoderm to form neural tissue therefore for many decades the view was that the default state of the ectoderm was to produce epidermis. The first challenges to this model came from studies making use of dissociated cell cultures (Sato and Sargent, 1989). It was found that when animal caps were cultured intact that epidermis formed but neural tissue arose from animal caps that had been dissociated for prolonged periods (as seen in Fig. 6 below). This led to the idea that intact tissue may block the formation of neural tissue by presence of neural inhibitors which are diluted out when the tissue is dissociated. Recent research has found that the default nature of the ectoderm is to produce neural tissue that requires inhibition of a neural inhibitor from the ectoderm. Before considering the process of neural induction I would like to take a step back and describe the three germ layers of the embryo. Following fertilisation, the zygote undergoes stages of cleavage to eventually form a gastrula with three germ layers (in triploblastic animals) usually only visible in vertebrate animals. The Germ layers will eventually give rise to all of the animals organs through a process known as organogenesis. The three layers include, the ectoderm (outermost), endoderm (innermost) and mesoderm (which is between the ectoderm and endoderm) layers. The Endoderm gives rise to the lung, thyroid and pancreas. The mesoderm forms the skeleton, skeletal muscle, the urogenital system, heart and blood. The outermost layer, the ectoderm which is of concern here, gives rise to the epidermis and nervous system. It is at gastrulation that the vertebrate ectoderm is competent to differentiate into neural tissue or epidermis. Unless told otherwise, the default nature of the ect oderm is to produce neural tissue and this was outlined as the default model. The Default model of vertebrate neural induction, discovered over a decade ago in Xenopus, proposed that in the presence of bone morphogenetic protein (BMP), a signalling molecule of the TGF-ÃŽ ² superfamily, causes the ectoderm to give rise to an epidermal cell fate (Stern, 2006; Muà ±oz-Sanjuan and Brivanlou, 2002). In support of this model, consistent with the idea that BMP activity inhibits neural fates, animal caps which had been injected with RNA encoding effectors of BMP4 (Smad 1/5 or Msx1) neuralization did not occur. Conversely, it was found that inhibition of BMP activity in the ectoderm is essential for a neural fate which forms the basis of the default model of neural induction. Inhibition of BMP is achieved through direct binding of BMP antagonists emitted from the organizer (Wilson and Hemmati-Brivanlou, 1997). These BMP antagonists include chordin (Sasai et al., 1995), noggin (Lamb et al., 1993) and follistatin (Hemmati-Brivanlou et al., 1994) which bind to BMPs extra cellularly to prevent its interaction with its own receptor (Hemmati-Brivanlou and Melton, 1997). These molecules have direct neural activity which means they induce formation of neural tissue in the ectoderm without forming mesoderm. It was initially believed that these molecules acted as ligands to bring about neural tissue formation. Experiments found that there was conservation through species, identifying that chordin was homologous to the short gastrulation (sog) gene found in Drosophila which has been shown to antagonize the BMP homologue decapentaplegic (dpp) (Wharton et al., 1993), suggesting that these molecules might act as inhibitors rather than inducers and that these inhibitory mechanisms have been conserved from arthropods through to vertebrates. It was experiments (Fig. 6) showing that dissociated ectodermal explants would become neural tissue in absence of inducing signals from the organizer (Sato and Sargent, 1989). Evidence found that neural induction resulted from inhibition of the TGF-ÃŽ ² pathway as expression of dominant-negative activin receptor gave rise to neural fates in amphibian ectoderms (Hemmati-Brivanlou and Melton, 1994). It was found that chordin, noggin, follistatin and molecules such as Cerberus and Xnr3 (Xenopus nodal related 3) bound to BMP in the extracellular space inhibiting its action (Hemmati-Brivanlou and Melton, 1997) leading to the much debated default model of neural induction. Neural Induction: FGFs get it started Support for the default model still remains, mainly in Xenopus, but other work (especially in chick and mouse) suggests a more complex mechanism (Streit et al., 1998). It has been established that the BMP pathway is involved in determining ectodermal cell fate (Wilson and Hemmati-Brivanlou, 1997) but it still remains to be proved conclusive if BMP inhibition is required for neural induction alone or if other pathways act separately or with BMP inhibition. In the chick embryo it has been found that naive epiblast cells do not respond to BMP antagonists until previous exposure to organizer signals for five hours (Streit et al., 1998). Striet et al. (2000) grafted an organizer to observe the genes induced in the epiblast within this time period. A gene ERNI (early response to neural induction) was identified as a coiled coil domain with a tyrosine phosphorylation site and found to be expressed throughout the region that later contributes to the nervous system at pre-primitive streak stages (Hatada and Stern, 1994). Striet et al. (2000) findings made ERNI the earliest known marker after a response to organizer signals, prior to even Sox3 (induced by the node in 3 hours (Streit and Stern, 1999)). FGFs are becoming more evident that they have a major role in neural induction as it has been shown to begin before gastrulation, before BMP antagonists even appear (Wilson et al., 2000). In the chick, it has been found that FGFs have the role of blocking BMP signalling and promoting neural differentiation (Wilson et al., 2000). In ascidians, FGF signalling is the main mechanism of neural induction with BMP antagonism playing a role in later development (Lemaire et al., 2002). In frogs and fish, in contrast, FGFs do not have a certain role in neural induction and is believed their primary role is BMP inhibition (Pera et al., 2003). Exposure of the chick epiblast to an implanted organiser for around 5 hours induces Sox3 (an early neural plate marker) (Stern, 2005). After removal of the implanted organiser, chordin can be used to stabilise it (Striet et al., 1998) which implies that before the ectoderm can respond to BMP antagonists it must be exposed to 5 hours of signals from the organizer. During these 5 hours, several genes become activated such as, ERNI (early response to neural induction) which becomes active after 1 hour (Streit et al., 2000) and Churchill (Chch) after about 4 hours (Sheng et al., 2003). These are both induced by FGF and not BMP inhibition, indicating the importance of FGFs in early neural induction. Churchill which is expressed in the neural plate inhibits brachyury, a transcription factor, which as a result suppresses mesoderm formation by preventing cell ingression. In the chick, FGF8 is expressed in the hypoblast, prior to gastrulation before Hensens node appears (the chick equivalent to the organizer) indicating that neural induction is in fact able to begin before gastrulation. This is important because ERNI and Sox3 mark neural induction and require FGF signalling (Stern, 2005). Streit et al. (2000) found that FGF8 coated beads induce ERNI as efficiently as the node within 1-2 h without inducing brachury and also the expression of Sox3. These results indicate FGFs to be possible early signals in neural induction. It is FGF8 which has been identified as the best candidate because it is expressed in the anterior part of the str

Comparing the Use of Light and Dark by Melville, Poe, and Hawthorne Ess

Use of Darkness and Light by Melville, Poe, and Hawthorne Melville, Poe, and Hawthorne all tend to focus on the darker side of humanity in their writings. In order to allow their readers to better understand their opinions, they often resort to using symbolism. Many times, those symbols take the form of darkness and light appearing throughout the story at appropriate times. A reader might wonder how light functions in the stories, and what it urges the reader to consider. If we look carefully at these appearances of light, or more likely the absence of it, we can gain some insight into what these "subversive romantics" consider to be the truth of humanity. Hawthorne uses this technique to its fullest; however, it is also very obvious in the stories of Poe and Melville. All of these authors have something to say about what they perceive as the breakdown of man and society - and they often clue us in by using differing degrees of light. The presence of darkness and light is probably the most apparent in Hawthorne's pieces, and "Young Goodman Brown" is an excellent example. The story starts off as Young Goodman Brown begins his trip into the forest, away from his wife, Faith. The first presence of light is in the first sentence: "Young Goodman Brown came forth at sunset ...." Now, there is light in the sun, but the significance lies in the fact that the sun is setting. The brightness in life - that is, the goodness of humanity that once existed, is now being taken over by the darkness. YGB then departs down a "dreary road, darkened by all the gloomiest trees of the forest." There is no mistaking this for anything but a symbol. YGB, representing all man, is going down a "narrow path" leading into one of the darkest and sca... ...aking of humanity): "this black conceit pervades him, through and through. You may be witched by his sunlight,--transported by the bright gildings in the skies he builds over you;--but there is the blackness of darkness beyond; and even his bright gildings but fringe, and play upon the edges of thunder-clouds." Â   Works Cited: Adler, Joyce. "Benito Cereno: Slavery and Violence in the Americas." Critical Essays in Herman Melville's Benito Cereno; Burkholder, Robert E., ed. Macmillan Publishing Co., NY, 1992. Gargano, James. "Art and Irony in William Wilson." New Approaches to Poe; Benton, Richard P., ed., 1970. Levin, Harry. The Power of Blackness. New York, 1967. Melville, Herman. "Hawthorne and His Mosses." From The Literary World, August 17 and 24, 1850. Accessed at: http://eldred.ne.mediaone.net/nh/hahm.html on May 1, 2000. Â  

The New Normal Challenges Societal Issues

Ryan Murphy is known for his ability to keep things interesting, and in his new sitcom The New Normal he has not fallen short on that expectations. In this series Bryan and David, a happy gay couple living in L. A. with respectable jobs, seem to have everything except for the one thing they want most, a child. The couple hires Goldie, a young mother who had just left her adulterous husband in Ohio and ran away to L. A. with daughter, Shania, to start over and forget her old life, to be a surrogate mother for them.Jane, Goldie's conservative and overly bigoted grandmother, follows them against her granddaughter's wishes, causing an uproar in Goldie’s new life in the city because she is so disproving of Goldie’s decision to be a surrogate and Bryan and David’s lifestyle. Immediately after airing in September of 2012, the show was criticized tremendously. The people of the broadcasting network in Salt Lake City, Utah were so offended by the show that they went on to ban the show from their show time schedule. NBC Utah affiliate KSL-TV, the network which banned the show from airing in Utah, says that the show was â€Å"inappropriate on several dimensions. They went on to say that the dialogue was excessively rude and crude and the scenes were too explicit and the characterizations seem offensive. KSL-TV also insist that it challenges traditional family values and portrays bad role models. The trouble the show experienced from attempting to air in Utah was not the only trouble the show had endured. In July, before the show aired, One Million Moms publicly announced that they would be boycotting the show for being harmful to our society, accusing the dialogue of being too offensive.Many members of the gay community also claimed to be boycotting the show for portraying offensive stereotypes of homosexuals. I must admit that I can see how the dialogue seems excessively crude and offensive. For example, in the pilot alone Jane uses the offensive ph rases; â€Å"gay peacocks†, â€Å"ass campers†, â€Å"Jewed done the cost†, and â€Å"salami smokers†. It’s easy to see how people could take her bigoted words offensively. It’s obvious from her first scene in the show that her prejudices are very overzealous and over the top but that is precisely the point.Nana seems as a nasty, hateful woman who has a potty mouth that anyone with a moral conscience would not want to replicate. Jane is used to show a societal problem in America today. A discussion of her behavior through the show should be of interest to more than just the fans and critics. Beyond these limited audiences, Nana is relevant to everyone in America because her bigotry was used by Ryan Murphy to display a nasty problem in our nation today. Her prejudice towards everyone that surrounds her is a mockery of many bigoted minds of Americans.Indeed, it does seem excessive, but Murphy wanted to make sure the point of how offensive and wrong this behavior is was clear. While I see how this crass behavior and crude dialogue is inappropriate for children, the show is a somewhat late night sitcom with a target audience of adults. As adults who have experienced shows with far worse dialogues such as Jersey Shore, we should be able to stomach the harmless dialogue of The New Normal especially when there is such an important point behind it. Shows like Jersey Shore aren’t refused to air because of their horrible dialogues because of Americans’ love for their trash TV.I believe that point shows that the problem with this show is truly just bigotry towards gay couples having children not the dialogue, which is Murphy’s entire point of making this show. It’s not just about entertaining television, it’s about making a stance on the problematic issue in America of bigotry and prejudice. The complaints given to show that it challenges family values seems to stem from the fact that it isnâ₠¬â„¢t a traditional nuclear family that is headed by a man and woman. Many happen to have a major issue with gay couples creating a family. However, the show proves that the couple holds family values.Firstly and most importantly they know and show how much they will love and provide for their child. They also show many other important family values and attributes. For example Bryan shows what a great father he will be and the confidence he will instill in his child in the second episode â€Å"Sofa’s Choice† when he talks to Shania because she’s having trouble fitting in at her new school. Shania says â€Å"Those kids don’t get me at all† Bryan replies â€Å"When I was in school no one got me either. This might be hard to believe Shania but I didn’t always fit in like I do now.I always felt different just like you† Shania shouts â€Å"Bryan I’m a weirdo and I don’t want to be. I just want to be normal. † Bryan mat ter-of-factly says â€Å"That’s a stupid short sided wish. † Bryan then moves to the couch to sit beside Shania and puts his arm around her comfortingly and says â€Å"You don’t know this yet, but the most unique parts of you are also the ones that lead you to greatness. † Shania says â€Å"How come you get me but my own mom doesn’t? † Bryan says â€Å"Your mom may not completely get you, but she lets you be who you are and she loves you for it, and that’s what makes her a great mom.Don’t be afraid to be who you are, Shania because you’re spectacular. † This shows how supportive and problem solving he can be as a dad but also shows that he thinks it is very important for children to be accepted and loved no matter who they are and that they know it’s wonderful to be the person they are no matter what anyone else says. In the episode â€Å"Stay-at-home Dad† David and Bryan decide to send Goldie on a s pa vacation and request to babysit Shania while she is gone because they want to experience and prepare for being stay at home dads.While Goldie is gone David takes off time from his very important job as a doctor to wake up early to make her breakfast and study before taking her to school. This is an example of how he will be a responsible dad who will compromise the job he loves to take care of his kid. These are the family values and concern you must have for your children in order to be great parents, and while David and Bryan don’t have everything about parenting figured out ,because no one does before having children, they have the mindset, love, and values that can potentially make great parents.While the show does show some unexpected characters and a family with an unusual dynamic it is in no way lacking great role models. While the adult characters in no way lack their fair share of dysfunction they are also great role models for America and for the young girl in th e show Shania. The excerpt from the beginning of the previous paragraph is also a great example of how Bryan is an exceptional role model for Shania. Goldie while often times seems to act on a whim is a great role model.In the same episode Bryan and David decide that they want Goldie and Shania to live in their luxurious guest house instead of their frumpy little house. Goldie turns the house down because she didn’t earn it and she wants to be a successful independent woman to give her daughter a great example so that one day she can become one as well. The most confrontational adult in the show is Nana, Jane. While her bigotry is repulsive she does not lack other admirable qualities.Despite her overzealous prejudice that seems to constantly be spewing from her mouth, she is a strong independent woman and a great grandmother. When Goldie and Shania run away to California, Nana follows them and decides to stay even though she is disproving of Goldie’s decision and Bryan and David’s lifestyle because she cannot stand the thought of not being there to spend time with and protect her family. Nana also raised Goldie from eight years old when her daughter decided she didn’t want to and ran away. She also housed Goldie and Shania up until they ran away to California.All of those attributes are wonderful to have, but the most important is that she has always been there for her family no matter what. Which Goldie admits in the episode â€Å"The Para-New Normal†, the Halloween episode, after an argument they’ve had about Goldie moving back to Ohio. Goldie says â€Å"God Nana, sometimes you make me so crazy, you know that? The things you say. † Nana replies â€Å"I am what I am, I’m not about to change now. † Goldie recedes â€Å"Well, then I guess I need to remember that. When I saw you trick-or-treating tonight, the way you were with Shania.It made me think. You are the one person who has always been there for me. The only one actually. † Goldie goes on to remember when her Nana took her trick-or-treating every year when she was young because her mother wasn’t there. â€Å"I like to think that I’m a good mom, Nana, but I didn’t learn that from my mom. I learned it from you. Thank you for always being there for us. † Nana responds â€Å"Well, I couldn’t just leave you. † â€Å"Well of course you could have, but you didn’t. And even now that I’m all grown up with people and choices that you don’t understand still†¦. ou still haven’t left. † It may have taken Goldie a long time to realize it but her Nana is a great role model for her and in many of the same ways is for America. Even the child in this show is a great role model because she learns to be proud of who she is with the help of the adults around her and doesn’t try to hide her quirky ways which is a great thing to show America, becau se no one should ever be ashamed of who they are. Many people see The New Normal’s message to be that the new normal of families in America will be led by a gay couple.This however, is a misunderstanding. The New Normal’s message is that no matter how untraditional a family is it is still a family with the same amount of love and values as traditional families. In the pilot this was made clear by giving examples of many other untraditional families. It showed a midget woman who married a man of normal height and had a daughter who was 6 years old and almost taller than her mother, a single mom of two twin toddlers who was much older than most new mothers; in fact, she looks old enough to be their grandmother.They even go as far to mention examples from pop culture today such as Barack Obama and Mariah Carey, who were both raised by what Bryan refers to as â€Å"half-rican American† Grandmothers. When the show says â€Å"abnormal in the new normal† it is n ot to say that families led by gay couples in the only new normal but that none of these untraditional families should be seen as anything less than the average traditional family. The New Normal defies stereotypes in many different ways. Although the show does show one of the gay men as a very effeminate male, Bryan.Which is why I can understand why many people in the gay community show offense as they see this as portrayal of a stereotypical gay men. However Bryan’s character is meant to portray the writer of The New Normal, Ryan Murphy. I think the character is important to show that effeminate males do exists and to show Ryan Murphy’s side of things and how the bigotry of others has affected him. Murphy saw it was important to show his own personal experiences in the show which is why he decided to create a character based on himself.It is not as if the show portrays all gay men to be effeminate. Bryan’s partner, David, is a gay man who is the average guyâ⠂¬â„¢s guy with no interest in fashion, and the many other favored interest of his partner, the â€Å"stereotypical gay man. † David is a doctor who loves to watch football and play sports. While the show does show someone who does fit a stereotype, David’s character defies said stereotype because he is a gay man who this prejudice doesn’t apply to. The show also defies the common stereotype that all black people are content with being bottom feeders of society.Rocky, Bryan’s assistant, is a very accomplished black woman with very high aspirations and goals. She has come a long way from where she grew up in an impoverished home to become an assistant for a producer of a very famous TV show. She is an example of a much empowered black woman who has worked very hard to be successful. Though The New Normal is just a TV show, it provides a lens through which we can examine the societal problems of bigotry and prejudice. Indeed, many problems such as the way p eople throughout the show treat David and Bryan as if they are less than their equal in the show can be seen in real life.For example, many people in America today have shown their disapproval of homosexuals by not only denying them adoption and marriage equality but by going as far as committing hate crimes against them. But the prejudice in the show and in real life doesn’t stop there; it is directed at anyone who is different by race, sexuality, living conditions, and plenty of others thing. The point of this show is to show people that we are all humans with flaws and great qualities and that everyone should be treated equally. We do live in the land of the free after all.

Analysing the change in the role of the management accountant

This work is focused on critically measuring the doggedness of the alteration in the function of the direction comptroller from traditional accounting maps to that of a strategic contriver and concern spouse. The work of Johnson and Kaplan ( 1987 ) , titled â€Å" Relevance doomed † has prompted a drill-down on this research country. Though most of the research workers agree to the altering function of the direction comptroller ( Burns and Baldvinsdottir, 2005 ; Cooper and Dart 2009 ; Allot 2000 ; Chenhall and Langfield-Smith2007 ; Siegel1999 ; Kerby and Romine 2005 ; Vaivio1999 ; Ittner and Lacker2001 ; Ax and Bjornenak 2007 ; Bhimani 2006 ; Roslender and Hart 2002 ) . The importance the traditional function still remains critical to others, and should function to complement the new techniques or the alteration. ( Bromwich and Bhimani 1998 ; Burns et Al. 1999 ) . Others are of the position that history is still a relevant portion of the hereafter or the altering tendency. ( Fleischman and Funnell 2006 ; Luft 1997 ; Beaman and Richardson2007 ) .The type of organisation every bit good as the direction may besides find the nature of alteration. Yazdifar and Tsamenyi ( 2005 ) . This a lteration does non take the same signifier in organisations, but differs in form. Sulaiman and Mitchell ( 2005 ) . With the present economic miasma, some research workers are even recommending a return to the old ways: the traditional function, ( Baldvinsdottir et al ( 2009 ) . The first subdivision of this work will therefore reexamine these positions presented and seek to pull a comparing between these positions to see if the function of the direction comptroller has really changed and to what extent. This will be done pulling support from literatures. It will instantly be followed with some of the new roles the direction comptroller is taking up in organisations. Thereafter the place of traditional accounting pattern in this new tendency of events will be discussed. This will enable us to cognize where to put the traditional accounting function, whether it has lost its utility and should be wholly cast-off or should function to congratulate the new functions. Following to that, some of the new techniques in direction accounting that organisations are following, the factors that are driving the alteration in function every bit good as their significance to the new function will be discussed. Decisions will so be drawn as to the direction comptroller ‘s functions change.The altering function of the direction comptroller.Johnson and Kaplan ( 1987 ) are deemed to hold set the canvas in this statement with their book titled â€Å" Relevance lost: the rise and autumn of direction accounting. † These strong footings used by them has prompted or necessitated a batch of research work in this way. They argue that the bing signifier of direction accounting lacked the know-how to run into up with the dynamic concern environment. Their statement was supported by mentioning technological promotions, information engineering, every bit good as planetary and domestic competition as grounds doing the bing patterns inadequate. Harmonizing to an article published in the Journal of Accountancy ( Most Companies Want Their Certified public accountant to Be Business Strategists, Survey Says, 1996 ) , much more is now being demanded of the direction comptrollers within organisations. Their occupations are traveling beyond the readying of fiscal statements as accounts and reading are now required of them of the information they provide. The direction comptroller is consequently a â€Å" high-ranking determination support specializer † . Kerby and Romine ( 2005 ) argue that for direction comptrollers to stay a relevant portion of their organisations, there must be a alteration in accent from the traditional accounting patterns which involves the numeration, analysis, reading and presentation of fiscal information. They advocate that the direction comptroller should be versed with cognition about alterations impacting the concern of his organisation and imbibe qualities that would enable them map as fully fledged concern spouses. Smith ( 2007 ) opined that the focal point of the direction comptroller within organisations is now switching to the external environment. That the direction comptroller is no more uniformed of what happens externally to his organisation, He now looks both inwards and outwards. Cooper and Dart ( 2009 ) , give support to this position that, direction comptrollers are traveling from being information suppliers to back uping the determination devising. Siegel ( 1999 ) , noted that direction comptrollers were earlier now non involved in the existent decision-making procedure, but acted in support of the determination shapers and subsequently got informed of facts. But the function of the direction comptroller had changed and greater portion of their clip was being spent as internal advisers or concern analyst within their companies. Like most of the other authors he attributes this altering function to the promotion in engineering which he states has freed the direction comptroller from what he describes as â€Å" mechanical accounting † . He stated that the new function of the direction comptroller now involves a batch of direct contacts with people throughout their organisations, and that they are more involved in determination devising and cross-functional squads. This he termed development from functioning internal clients to being concern spouses.The direction comptroller as strategic contriver and concern spouse.The cardinal message of this work has been on the direction comptroller presuming the function of strategic contriver and concern spouse as opposed to the traditional function of corporate bull and bean counter. The direction comptroller ‘s function has evolved and is determining up into a strategic fiscal contriver and director of information. The direction comptroller is said to be h olding less to make with the everyday accounting pattern. ( Siegel 2000, Cooper and Dart, 2009, Latshaw, A. and Choi, Y. , 2000 ) . New countries of focal point of the direction accountant include the development of fiscal programs, information engineering systems direction, assisting in the formation of concern aims every bit good as monitoring consequences and maintaining up with selling aims. Others are direction and organisation of work force, playing consultative function in operational determinations, programmes and undertakings. ( Feeney and Pierce, 2007 ) . For the direction comptroller to work efficaciously as concern spouse, certain accomplishments must be acquired. This will include the quality of analysing and treating unwritten and numeral informations into meaningful information. This should be buttressed by the ability to work efficaciously in a squad. ( Curruth, 2004 ) As concern spouse, the direction comptroller combines both the traditional function of protecting the assets of the concern with a new function of analysis and engagement in determination devising in the concern disposal. ( Kennedy and Sorensen, 2006 ) . Caron ( 2006 ) , defined stairss that should be taken for the direction comptroller to presume the place of a concern spouse. They include: Acting as operation and cognition expert. He/she should be able to supply best pattern information and strategic accomplishments. Should be able to set to pattern the cognition acquired in developing strategic direction programs. He/she should be able to mobilise the human resources at his disposal. He/she should be able to circulate accounting information efficaciously.Management accounting the place of the traditional function.Although Johnson and Kaplan ( 1987 ) opined that the traditional accounting function of the direction comptroller had lost its value and have argued that it is no more relevant to the dynamism of today ‘s universe, non everyone believe their sentiment is best for direction accounting, and have therefore expressed their reserves. ( Bromich and Bhimani 1989 ; Burns et Al 1999 ; Yazdifar and Tsamenyi 2005 ) . Baldvinsdottir et Al. ( 2009 ) are of the sentiment that a return to the traditional or â€Å" mechanical † accounting methods is of great importance particularly at this period of economic down-turn. They argue that although the ballyhoo about the altering function of the direction comptroller, a batch of the traditional accounting function has comparatively remained the same over several decennaries. Luft ( 1997 ) is of the position that history serves as a platform for understanding the present ; that the oversights of the nowadays could really be alleviated by mentioning back to history. Fleischman and Funnell ( 2006 ) , while holding with Johnson and Kaplan, that it is of import that direction accounting studies provide direction with information that will help them in minimising cost and improved productiveness, argue that although these activities are frontward looking, they have to be based on what they described as â€Å" intimate dependance between the past and future † . They insist this is necessary because of the uncertainnesss and instabilities associated with commercial environments, coupled with the intricatsies of direction. That, direction comptrollers in the class of seeking to do the information they provide more utile to their organisations should bear in head that this should be done in observation of necessary ethical issues. Beaman and Richardson ( 2007 ) found out in their research that accounting patterns within organisations are being confined to the traditional function, alternatively of the expected function of determination support and job resolution. There has been the recognition of the broad usage of traditional accounting techniques in most organisations as opposed to the supposed outlook of radically new advanced accounting techniques being adopted by these organisations. ( Burns and Scapens, 2000 ) .Emerging techniques in direction accounting.Some comparatively new trends/techniques have emerged with the purpose of undertaking the insufficiencies of the traditional accounting methods. Some of them have been lauded as the new title-holders of direction accounting solution suppliers in organisations. ( Cooper and Kaplan, 1991 ) . Although these techniques are extremely praised, their acceptance and execution may non hold been as widely accepted as the ballyhoo associated with them. ( Collier and Gregory, 1995 ; Roslender and Hart, 2003 ) . These techniques include: Activity based costing ( ABC ) ; The coming of ABC has changed the pattern of cost allotment necessitating that direction accountants develop more analytical accomplishment to undertake the complexnesss of apportioning operating expenses to different cost objects utilizing cost drivers. ( Burns and Yazdifar, 2001 ; Byrne and Pierce, 2007 ; Anderson, 1995 ) . ABC made the direction comptroller an indispensable portion of the determination doing procedure by concentrating on pertinent information needed to better steadfast public presentation financially and market wise. ( Kennedy and Affleck-Graves, 2001 ) . Kaplan and Anderson ( 2004 ) nevertheless noted that organisations have abandoned ABC because of its failure to capture the complex nature of their operations, the holds of execution and the cost consequence which are normally excessively expensive. Balanced scorecard ( BSC ) : The balanced scorecard enables the direction comptroller to strategically mensurate public presentation and develop a model for the strategic measuring and direction systems ( Kaplan and Norton, 2007 ) . It changes accent from fiscal facet to encompassing client, internal and every bit good as acquisition and growing factors of organisations. ( Kaplan and Norton, 1996 ) . This has altered the function of the direction accountant puting him strategically as a determination support specializer. ( Latshaw and Choi, 2002 ) . BSCs are adopted by houses for strategic public presentation measuring, but the result of these steps is normally developed to encompass operational scheme, nevertheless it was noted that organisations frequently fail in seeking to set BCS into a peculiar usage ( Wiersma, 2009 ) . Atkinson ( 2006 ) noted that the BSC has been found deficient from empirical consequences of its benefits.Strategic direction accounting:Strategic direction acc ounting ( SMA ) : SMA shifts the focal point of direction comptroller to non-financial factors external to the organisation. ( Simmonds,1981 ) . It demands that the direction comptroller be knowing in subjects like public presentation indexs development, value concatenation analysis every bit good as capacity cost direction. It broadens the range of the direction accountant beyond the house to strategizing for competitory market and chances. ( Whiteley, 1995 ) . SMA requires the direction comptroller as a member of the cross functional squad which his function now embraces to convey to bear relevant information and expertness that will help determination devising. ( Roslender and Hart, 2001 ) . The direction comptroller now addresses the impact of other non-financial activities, the cost place of rivals, and rating of rival merchandises and services. These activities have placed the direction comptroller in the important function of strategic contriver and concern spouse. ( Whiteley , 1995 ; Langfield-Smith, 2008 ) . However, Roslender and Hart ( 2003 ) , noted that what constitutes strategic direction accounting is still non clearly defined. Collier and Gregory, ( 1995 ) opined that the degree of execution of strategic direction accounting may postpone in different economic systems. That is, the economic system determines the scheme and functionality of the direction comptrollers. Enterprise resource planning ( ERP ) : ERP requires the direction comptroller to hold sound cognition that will enable him to supply information that will technically run into the demands of the house. It besides demands that the MA be versed with cognition of concern maps related to production, selling and information engineering. For the direction comptroller to acquire traveling with all these maps, he needs to construct a sound inter-personal and societal accomplishments. ( Barton, 2009 ; Pierce and O'Dea, 2003 ) . It may nevertheless cut down occupations, making unemployment. Enterprise resource planning ( ERP ) : enables the direction comptroller to track â€Å" production by occupation, work centre, and activity † ( Zimmerman, 2009:720 ) . However, respondents to research carried out by Knnerley and Neely ( 2001 ) were non certain the debut of ERP to their organisations had made any noticeable impact.Factors driving the alteration in the function of direction accounting.The utility of direction accounting has come under examination following factors like: mechanization of mill procedures and processs, information engineering, competition, and globalisation, complexness of concern among others. Some of these factors and their significance will be discussed briefly. Information Technology: ( Carruth, 2004 ; Beaman and Richardson, 2007 ) , noted that information engineering has enabled direction comptrollers to take more responsible functions in their organisations. The direction comptroller is now able to salvage clip in his analysis and reading of information. The direction comptroller helps in showing informations in a signifier that makes them relevant and utile for managerial intent. This involves strategizing and being involved in the determination devising procedure. Granlund, M. and Malmi, T. ( 2002 ) It has changed the nature of information and placed determination doing on information provided by the direction comptroller. ( Atkinson et al. 1999 ) . Automation ; requires the direction comptroller to develop more analytical accomplishments and to be able to supply such information that will enable houses take determinations and follow such schemes that will assist them remain in competition. ( Kerremans et al. , 1991 ) . Automation is advantageous in take downing labor cost, but may make occupation losingss. ( Mantripragada and Sweeney, 1981 ) .Other factors:Other noteworthy factors driving the function alteration in direction accounting include ; the accent on quality, rational capital, more client focused organisations, addition in overhead cost, less of direct labor cost, and precedence on environmental and external issues. These factors have helped orient the direction comptroller ‘s function to that of a strategic contriver and a concern spouse. The direction comptroller now takes a more proactive function in cognizing and supplying solutions to strategic issues in his organisation. The issue of competitory concern env ironment which is closely related to globalisation is another major factor impacting the manner direction accounting maps are handled in organisations.DecisionAlthough there have been demands for the alteration in accent on the function of direction comptroller, this alteration has non been absolute. This is because the cost and complexness of using these new techniques have made their acceptance slow. The debut of new techniques in direction accounting and the impact of assorted factors have made the direction comptroller more focussed on non-financial facets of organisations and has widened the range of activities external to the organisation, doing him a utile portion of the determination devising procedure. However recent issues ‘ following the economic downswing has suggested keeping of portion of the traditional function in combination with new techniques might be more utile. ( Balvinsdottir et al. , July/Aug. 2009 ) Furthermore, the importance of these new techniques and the benefit they provide to organisations can non be overemphasized. These new inventions have made the direction comptroller more flexible, a solution supplier and an of import portion of the organisation as concern spouse and strategian, reconstructing relevancy. ( Johnson, 1992 ) . It is notable that though many are the advantages of implementing these new techniques, some organisations still stick to traditional accounting because it is less complex to implement, salvaging clip.